Scholars@UK
Surface-based morphometry reveals divergent aging trajectories in veterans with and without traumatic brain injury
for the Alzheimer’s Disease Neuroimaging Initiative, 2025, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Article › peer-review
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory decline
for the Alzheimer’s Disease Neuroimaging Initiative, Aug 2025, In: GeroScience. 47, 4, p. 5825-5842 18 p.Research output: Contribution to journal › Article › peer-review
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume
Alzheimer’s Disease Neuroimaging Initiative (ADNI) & Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Jun 2022, In: GeroScience. 44, 3, p. 1807-1823 17 p.Research output: Contribution to journal › Article › peer-review
Dynamic proportional loss of functional connectivity revealed change of left superior frontal gyrus in subjective cognitive decline: an explanatory study based on Chinese and Western cohorts
for the Alzheimer’s Disease Neuroimaging Initiative, Aug 2025, In: GeroScience. 47, 4, p. 5619-5634 16 p.Research output: Contribution to journal › Article › peer-review
Local molecular and connectomic contributions of tau-related neurodegeneration
for the Alzheimer’s disease Neuroimaging Initiative (ADNI), Feb 2025, In: GeroScience. 47, 1, p. 227-246 20 p.Research output: Contribution to journal › Article › peer-review
Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia prediction
Alzheimer’s Disease Neuroimaging Initiative Consortium, Apr 2025, In: GeroScience. 47, 2, p. 2099-2118 20 p.Research output: Contribution to journal › Article › peer-review
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
Alzheimer’s Disease Neuroimaging Initiative, Dec 2023, In: Communications Medicine. 3, 1, 49.Research output: Contribution to journal › Article › peer-review
Impact of amyloid and cardiometabolic risk factors on prognostic capacity of plasma neurofilament light chain for neurodegeneration
for the Alzheimer’s Disease Neuroimaging Initiative, Dec 2024, In: Alzheimer's Research and Therapy. 16, 1, 202.Research output: Contribution to journal › Article › peer-review
Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer’s disease
Alzheimer’s Disease Neuroimaging Initiative Consortium, Dec 2024, In: GeroScience. 46, 6, p. 6071-6084 14 p.Research output: Contribution to journal › Article › peer-review
Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort
Oka, T., Matsuzawa, Y., Tsuneyoshi, M., Nakamura, Y., Aoshima, K., Tsugawa, H., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Liu, E. & Montine, T. & 278 others, , Dec 2024, In: Scientific Reports. 14, 1, 6797.Research output: Contribution to journal › Article › peer-review
Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease
for the ADNI, Jun 2023, In: International Journal of Geriatric Psychiatry. 38, 6, e5952.Research output: Contribution to journal › Article › peer-review
A data-driven examination of apathy and depressive symptoms in dementia with independent replication
for the Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 1, e12398.Research output: Contribution to journal › Article › peer-review
Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease
Alzheimer’s Disease Neuroimaging Initiative & the Swedish BioFinder Study, Dec 2020, In: Nature Communications. 11, 1, 2612.Research output: Contribution to journal › Article › peer-review
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dominantly Inherited Alzheimer Network (DIAN) Study Group & Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer’s Disease (PREVENT-AD) Research Group, Dec 2021, In: Nature Communications. 12, 1, 5346.Research output: Contribution to journal › Article › peer-review
A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure
iSTAGING Consortium, Baltimore Longitudinal Study of Aging (BLSA) & Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 2021, In: Nature Communications. 12, 1, 7065.Research output: Contribution to journal › Article › peer-review
Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease
Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 2022, In: Nature Communications. 13, 1, 1495.Research output: Contribution to journal › Article › peer-review
The trend of disruption in the functional brain network topology of Alzheimer’s disease
for the Alzheimer’s Disease Neuroimaging Initiative, Dec 2022, In: Scientific Reports. 12, 1, 14998.Research output: Contribution to journal › Article › peer-review
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease
Alzheimer’s Disease Neuroimaging Initiative, Jul 2022, In: Nature Aging. 2, 7, p. 616-634 19 p.Research output: Contribution to journal › Article › peer-review
Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment
for the Alzheimer’s Disease Neuroimaging Initiative, Aug 2022, In: GeroScience. 44, 4, p. 2319-2336 18 p.Research output: Contribution to journal › Article › peer-review
Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease (Nature Communications, (2020), 11, 1, (2612), 10.1038/s41467-020-15701-2)
Alzheimer’s Disease Neuroimaging Initiative & the Swedish BioFinder Study, Dec 1 2021, In: Nature Communications. 12, 1, 4862.Research output: Contribution to journal › Comment/debate
The Alzheimer's Biomarker Consortium - Down Syndrome (ABC-DS) -- DSU19 Core
Schmitt, F. (PI), Harp, J. (CoI), Jicha, G. (CoI), King, R. (CoI), Lightner, D. (CoI) & Koehl, L. (Former CoI)
9/30/20 → 8/31/26
Project: Research project
Clinical Core: University of Kentucky Alzheimer's Disease Research Center
Jicha, G. (PI), Caudill, T. (CoI), Coskun, E. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), King, R. (CoI), Schmitt, F. (CoI) & Van Eldik, L. (CoI)
8/1/21 → 6/30/26
Project: Research project
University of Kentucky Alzheimer's Disease Research Center
Van Eldik, L. (PI), Abner, E. (CoI), Bahrani, A. (CoI), Braun, D. (CoI), Caudill, T. (CoI), Cheng, Q. (CoI), Choucair, I. (CoI), Coskun, E. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Lee, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Reschke-Hernandez, A. E. (CoI), Rhodus, E. (CoI), Schmitt, F. (CoI), Selenica, M.-L. (CoI), Wang, W. (CoI), Whitehurst, L. (CoI), Yamasaki, T. (CoI), Zachariou, V. (CoI), Bieberich, E. (Former CoI), Gibson, A. (Former CoI), Johnson, N. (Former CoI), Kryscio, R. (Former CoI), Moga, D. (Former CoI), Wilcock, D. (Former CoI) & Wilson, D. (Former CoI)
8/1/21 → 6/30/26
Project: Research project
Clinical Core: University of Kentucky Alzheimer's Disease Research Center
Jicha, G. (PI), Caudill, T. (CoI), Coskun, E. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), King, R. (CoI), Schmitt, F. (CoI) & Van Eldik, L. (CoI)
8/1/21 → 6/30/25
Project: Research project
University of Kentucky Alzheimer's Disease Research Center
Van Eldik, L. (PI), Abner, E. (CoI), Bahrani, A. (CoI), Braun, D. (CoI), Caudill, T. (CoI), Cheng, Q. (CoI), Choucair, I. (CoI), Coskun, E. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Lee, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Reschke-Hernandez, A. E. (CoI), Rhodus, E. (CoI), Schmitt, F. (CoI), Selenica, M.-L. (CoI), Wang, W. (CoI), Whitehurst, L. (CoI), Yamasaki, T. (CoI), Zachariou, V. (CoI), Bieberich, E. (Former CoI), Gibson, A. (Former CoI), Johnson, N. (Former CoI), Kryscio, R. (Former CoI), Moga, D. (Former CoI), Wilcock, D. (Former CoI) & Wilson, D. (Former CoI)
8/1/21 → 6/30/25
Project: Research project
The Alzheimer's Biomarker Consortium - Down Syndrome (ABC-DS) -- DSU19 Core
Schmitt, F. (PI), Harp, J. (CoI), Jicha, G. (CoI), King, R. (CoI), Lightner, D. (CoI) & Koehl, L. (Former CoI)
9/30/20 → 8/31/25
Project: Research project
ADNI4: Alzheimer's Disease Neuroimaging Initiative 4
King, R. (PI)
University of Southern California
9/15/22 → 7/31/27
Project: Research project
Clinical Core University of Kentucky Alzheimer's Disease Research Center
Jicha, G. (PI), Caudill, T. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), King, R. (CoI), Schmitt, F. (CoI) & Van Eldik, L. (CoI)
8/1/21 → 6/30/24
Project: Research project
University of Kentucky Alzheimer's Disease Research Center
Van Eldik, L. (PI), Abner, E. (CoI), Bahrani, A. (CoI), Bieberich, E. (CoI), Caudill, T. (CoI), Cheng, Q. (CoI), Choucair, I. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Rhodus, E. (CoI), Schmitt, F. (CoI), Selenica, M.-L. (CoI), Wang, W. (CoI), Whitehurst, L. (CoI), Wilson, D. (CoI), Zachariou, V. (CoI), Gibson, A. (Former CoI), Johnson, N. (Former CoI), Moga, D. (Former CoI) & Wilcock, D. (Former CoI)
8/1/21 → 6/30/24
Project: Research project
The Alzheimer's Biomarker Consortium - Down Syndrome (ABC-DS) -- DSU19 Core
Schmitt, F. (PI), Harp, J. (CoI), Jicha, G. (CoI), King, R. (CoI), Koehl, L. (CoI) & Lightner, D. (CoI)
9/30/20 → 8/31/23
Project: Research project
Clinical Core University of Kentucky Alzheimer's Disease Research Center
Jicha, G. (PI), Caudill, T. (CoI), Gibson, A. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Johnson, N. (CoI), King, R. (CoI), Moga, D. (CoI), Schmitt, F. (CoI) & Whitehurst, L. (CoI)
8/1/21 → 6/30/23
Project: Research project
University of Kentucky Alzheimer's Disease Research Center
Van Eldik, L. (PI), Abner, E. (CoI), Bahrani, A. (CoI), Caudill, T. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Schmitt, F. (CoI), Selenica, M.-L. (CoI), Wang, W. (CoI), Whitehurst, L. (CoI), Wilson, D. (CoI) & Wilcock, D. (Former CoI)
8/1/21 → 6/30/23
Project: Research project
Data Core Scope: University of Kentucky Alzheimer's Disease Research Center
Kryscio, R. (PI), Abner, E. (CoI), Bardach, S. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Schmitt, F. (CoI), Van Eldik, L. (CoI), Wilcock, D. (CoI), Wilson, D. (CoI) & Hubbard, H. (Former CoI)
8/1/21 → 6/30/22
Project: Research project
Biomarker Core Scope: University of Kentucky Alzheimer's Disease Research Center
Wilcock, D. (PI), Abner, E. (CoI), Bardach, S. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Schmitt, F. (CoI), Van Eldik, L. (CoI), Wilson, D. (CoI) & Hubbard, H. (Former CoI)
8/1/21 → 6/30/22
Project: Research project
Research Education Core Scope: University of Kentucky Alzheimer's Disease Research Center
Van Eldik, L. (PI), Abner, E. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Schmitt, F. (CoI), Wilcock, D. (CoI), Wilson, D. (CoI), Bardach, S. (Former CoI) & Hubbard, H. (Former CoI)
8/1/21 → 6/30/22
Project: Research project
Outreach, Recruitment and Engagement Core Scope: University of Kentucky Alzheimer's Disease Research Center
Schmitt, F. (PI), Abner, E. (CoI), Bardach, S. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Van Eldik, L. (CoI), Wilcock, D. (CoI), Wilson, D. (CoI) & Hubbard, H. (Former CoI)
8/1/21 → 6/30/22
Project: Research project
Neuropathology Core Scope: University of Kentucky Alzheimer's Disease Research Center
Nelson, P. (PI), Abner, E. (CoI), Bardach, S. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Jicha, G. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Schmitt, F. (CoI), Van Eldik, L. (CoI), Wilcock, D. (CoI), Wilson, D. (CoI) & Hubbard, H. (Former CoI)
8/1/21 → 6/30/22
Project: Research project
Clinical Core Scope: University of Kentucky Alzheimer's Disease Research Center
Jicha, G. (PI), Abner, E. (CoI), Bardach, S. (CoI), Cheng, Q. (CoI), Ebbert, M. T. W. (CoI), El Khouli, R. (CoI), Fardo, D. (CoI), Gibson, A. (CoI), Gold, B. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), Johnson, N. (CoI), Katsumata, Y. (CoI), King, R. (CoI), Kryscio, R. (CoI), Lee, D. (CoI), Moga, D. (CoI), Nelson, P. (CoI), Neltner, J. (CoI), Powell, D. (CoI), Schmitt, F. (CoI), Van Eldik, L. (CoI), Wilcock, D. (CoI), Wilson, D. (CoI) & Hubbard, H. (Former CoI)
8/1/21 → 6/30/22
Project: Research project
Jicha Core B - University of Kentucky Alzheimer's Disease Core Center
Jicha, G. (PI), King, R. (CoI), Murphy, R. (CoI), Schmitt, F. (CoI), Van Eldik, L. (CoI) & Caban-Holt, A. (Former CoI)
7/15/06 → 6/30/21
Project: Research project
Jicha Core B - University of Kentucky Alzheimer's Disease Core Center
Jicha, G. (PI), Caban-Holt, A. (CoI), King, R. (CoI), Murphy, R. (CoI), Schmitt, F. (CoI) & Van Eldik, L. (CoI)
7/15/06 → 6/30/20
Project: Research project
Associated Departments